The Premier League leaders wrapped up their pursuit of Juan Cuadrado on Monday and former Basel man Salah has now been given the greenlight to move to Florence until at least the end of the season.
The 22-year-old has struggled for first-team opportunities since moving to west London a year ago despite initially made a promising start to life at the club, notably scoring in last season's 6-0 win over Arsenal.
But he has made just three appearances in the Premier League this term, all off the bench, and was entirely omitted from Jose Mourinho's matchday squad on 14 occasions.
Now Salah has a chance to revive his career in Serie A, where it will be hoped he can replace the output of talisman Cuadrado, who bagged four goals and four assists before making his switch to the Premier League.
Speaking about the deal last week, Fiorentina boss Vincenzo Montella said: "It was a sale that had to be done. The club has done the right thing because we are also getting a very good player in return.
"Naturally, we need to understand how long [Salah] will need to adapt to our football as it's different from the English and Swiss leagues. From a defensive standpoint, Cuadrado guarantees us a lot more than Salah."
